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Select item 60424221.

Development of a laboratorial platform for diagnosis of schistosomiasis mansoni by PCR-ELISA

Carolina Senra, Luciana Inácia Gomes, Liliane Maria Vidal Siqueira, Paulo Marcos Zech Coelho, Ana Rabello, Edward Oliveira

BMC Res Notes. 2018; 11: 455. Published online 2018 Jul 11. doi: 10.1186/s13104-018-3571-7

PMCID:: PMC6042422

Abstract Article PDF–1004K

Select item 79908922.

Previous History of American Tegumentary Leishmaniasis Alters Susceptibility and Immune Response Against Schistosoma mansoni Infection in Humans

Guilherme Silva Miranda, Samira Diniz Resende, Diogo Tavares Cardoso, Genil Mororó Araújo Camelo, Jeferson Kelvin Alves Oliveira Silva, Vanessa Normandio de Castro, Stefan Michael Geiger, Mariângela Carneiro, Deborah Negrão-Corrêa

Front Immunol. 2021; 12: 630934. Published online 2021 Mar 11. doi: 10.3389/fimmu.2021.630934

PMCID:: PMC7990892

Abstract Article PDF–1.2M

Select item 88936803.

Schistosoma mansoni infection induces plasmablast and plasma cell death in the bone marrow and accelerates the decline of host vaccine responses

Fungai Musaigwa, Severin Donald Kamdem, Thabo Mpotje, Paballo Mosala, Nada Abdel Aziz, De’Broski R. Herbert, Frank Brombacher, Justin Komguep Nono

PLoS Pathog. 2022 Feb; 18(2): e1010327. Published online 2022 Feb 14. doi: 10.1371/journal.ppat.1010327

PMCID:: PMC8893680

Abstract Article PDF–2.0M

Select item 80055464.

Schistosomiasis Morbidity Hotspots: Roles of the Human Host, the Parasite and Their Interface in the Development of Severe Morbidity

Patrice A. Mawa, Julien Kincaid-Smith, Edridah M. Tukahebwa, Joanne P. Webster, Shona Wilson

Front Immunol. 2021; 12: 635869. Published online 2021 Mar 12. doi: 10.3389/fimmu.2021.635869

PMCID:: PMC8005546

Abstract Article PDF–1.1M

Select item 90991095.

Noninvasive diagnosis of periportal fibrosis in schistosomiasis mansoni: A comprehensive review

Joelma Carvalho Santos, Caroline Louise Diniz Pereira, Ana Lúcia Coutinho Domingues, Edmundo Pessoa Lopes

World J Hepatol. 2022 Apr 27; 14(4): 696–707. Published online 2022 Apr 27. doi: 10.4254/wjh.v14.i4.696

PMCID:: PMC9099109

Abstract Article PDF–1.8M

Select item 93285646.

Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection

Joseph Bertin Kadji Fassi, Hermine Boukeng Jatsa, Ulrich Membe Femoe, Valentin Greigert, Julie Brunet, Catherine Cannet, Christian Mérimé Kenfack, Nestor Gipwe Feussom, Emilienne Tienga Nkondo, Ahmed Abou-Bacar, Alexander Wilhelm Pfaff, René Kamgang, Pierre Kamtchouing, Louis-Albert Tchuem Tchuenté

PLoS Negl Trop Dis. 2022 Jul; 16(7): e0010249. Published online 2022 Jul 15. doi: 10.1371/journal.pntd.0010249

PMCID:: PMC9328564

Abstract Article PDF–6.9M

Select item 50686987.

Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni

Thiago Almeida Pereira, Wing-Kin Syn, Frederico Figueiredo Amâncio, Pedro Henrique Diniz Cunha, Julia Fonseca Morais Caporali, Guilherme Vaz de Melo Trindade, Elisângela Trindade Santos, Márcia Maria Souza, Zilton Araújo Andrade, Rafal P Witek, William Evan Secor, Fausto Edmundo Lima Pereira, José Roberto Lambertucci, Anna Mae Diehl

PLoS Negl Trop Dis. 2016 Oct; 10(10): e0005057. Published online 2016 Oct 18. doi: 10.1371/journal.pntd.0005057

PMCID:: PMC5068698

Abstract Article PDF–1.7M

Select item 94482538.

Spatial distribution of the positivity of Schistosomiasis mansoni in Maranhao State, Northeastern Brazil, from 2007 to 2016

Renato Juvino de Aragão Mendes, Selma Patrícia Diniz Cantanhede, Adalberto Alves Pereira, Filho, Aline de Jesus Lustosa Nogueira, Isaias Pereira da Silva, Ivone Garros Rosa

Rev Inst Med Trop Sao Paulo. 2022; 64: 053. Published online 2022 Sep 5. doi: 10.1590/S1678-9946202264053

PMCID:: PMC9448253

Abstract Article PDF–2.6M

Select item 90640939.

Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection

Ulrich Membe Femoe, Hermine Boukeng Jatsa, Valentin Greigert, Julie Brunet, Catherine Cannet, Mérimé Christian Kenfack, Nestor Gipwe Feussom, Joseph Bertin Kadji Fassi, Emilenne Tienga Nkondo, Ahmed Abou-Bacar, Alexander Wilhelm Pfaff, Théophile Dimo, Pierre Kamtchouing, Louis-Albert Tchuem Tchuenté

PLoS Negl Trop Dis. 2022 Apr; 16(4): e0010382. Published online 2022 Apr 21. doi: 10.1371/journal.pntd.0010382

PMCID:: PMC9064093

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Select item 472028410.

Sustaining Control of Schistosomiasis Mansoni in Western Côte d’Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration

Rufin K. Assaré, Yves-Nathan T. Tian-Bi, Patrick K. Yao, Nicaise A. N’Guessan, Mamadou Ouattara, Ahoua Yapi, Jean T. Coulibaly, Aboulaye Meïté, Eveline Hürlimann, Stefanie Knopp, Jürg Utzinger, Eliézer K. N’Goran

PLoS Negl Trop Dis. 2016 Jan; 10(1): e0004329. Published online 2016 Jan 20. doi: 10.1371/journal.pntd.0004329

PMCID:: PMC4720284

Abstract Article PDF–2.0M

Select item 960755311.

Schistosomiasis Mansoni-Recruited Eosinophils: An Overview in the Granuloma Context

Kássia K. Malta, Cinthia Palazzi, Vitor H. Neves, Yasmin Aguiar, Thiago P. Silva, Rossana C. N. Melo

Microorganisms. 2022 Oct; 10(10): 2022. Published online 2022 Oct 13. doi: 10.3390/microorganisms10102022

PMCID:: PMC9607553

Abstract Article PDF–2.4M

Select item 565598412.

Schistosomiasis mansoni incidence data in Rwanda can improve prevalence assessments, by providing high-resolution hotspot and risk factors identification

E. Nyandwi, A. Veldkamp, S. Amer, C. Karema, I. Umulisa

BMC Public Health. 2017; 17: 845. Published online 2017 Oct 25. doi: 10.1186/s12889-017-4816-4

PMCID:: PMC5655984

Abstract Article PDF–4.5M

Select item 634013413.

The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni

Gilmara Lima Nascimento, Helio Milani Pegado, Ana Lúcia Coutinho Domingues, Ricardo Arraes de Alencar Ximenes, Alexander Itria, Luciane Nascimento Cruz, Maria Regina Fernandes de Oliveira

Mem Inst Oswaldo Cruz. 2019; 114: e180347. Published online 2019 Jan 14. doi: 10.1590/0074-02760180347

PMCID:: PMC6340134

Abstract Article PDF–300K

Select item 1069173014.

Can antibody conjugated nanomicelles alter the prospect of antibody targeted therapy against schistosomiasis mansoni?

Eglal I. Amer, Sonia R. Allam, Aceel Y. Hassan, Esmail M. El-Fakharany, Mona M. Agwa, Sherine N. Khattab, Eman Sheta, Marwa H. El-Faham

PLoS Negl Trop Dis. 2023 Dec; 17(12): e0011776. Published online 2023 Dec 1. doi: 10.1371/journal.pntd.0011776

PMCID:: PMC10691730

Abstract Article PDF–6.1M

Select item 455831415.

Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Thiago A. Pereira, Wing-Kin Syn, Mariana V. Machado, Paula V. Vidigal, Vivian Resende, Izabela Voieta, Guanhua Xie, Alba Otoni, Márcia M. Souza, Elisângela T. Santos, Isaac S. Chan, Guilherme V.M. Trindade, Steve S. Choi, Rafal P. Witek, Fausto E. Pereira, William E. Secor, Zilton A. Andrade, José Roberto Lambertucci, Anna Mae Diehl

Clin Sci (Lond) 2015 Nov 1; 129(10): 875–883. Prepublished online 2015 Jul 21. Published online 2015 Sep 1. doi: 10.1042/CS20150117

PMCID:: PMC4558314

Abstract Article PDF–1.5M

Select item 829343316.

Schistosomiasis with a Focus on Africa

Oyime Poise Aula, Donald P. McManus, Malcolm K. Jones, Catherine A. Gordon

Trop Med Infect Dis. 2021 Sep; 6(3): 109. Published online 2021 Jun 22. doi: 10.3390/tropicalmed6030109

PMCID:: PMC8293433

Abstract Article PDF–1.3M

Select item 749335317.

Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni

Maha M. Eissa, Mervat Z. El-Azzouni, Labiba K. El-Khordagui, Amany Abdel Bary, Riham M. El-Moslemany, Sara A. Abdel Salam

Parasit Vectors. 2020; 13: 474. Published online 2020 Sep 15. doi: 10.1186/s13071-020-04346-1

PMCID:: PMC7493353

Abstract Article PDF–2.0M

Select item 432059218.

Sustaining control of schistosomiasis mansoni in moderate endemicity areas in western Côte d’Ivoire: a SCORE study protocol

Rufin K Assaré, Stefanie Knopp, Nicaise A N’Guessan, Ahoua Yapi, Yves-Nathan T Tian-Bi, Patrick K Yao, Jean T Coulibaly, Mamadou Ouattara, Aboulaye Meïté, Alan Fenwick, Eliézer K N’Goran, Jürg Utzinger

BMC Public Health. 2014; 14: 1290. Published online 2014 Dec 17. doi: 10.1186/1471-2458-14-1290

PMCID:: PMC4320592

Abstract Article PDF–1.1M

Select item 351874019.

Macrophage-derived Hedgehog Ligands Promotes Fibrogenic and Angiogenic Responses in Human Schistosomiasis mansoni

Thiago A. Pereira, Guanhua Xie, Steve S. Choi, Wing-Kin Syn, Izabela Voieta, Jiuyi Lu, Isaac S. Chan, Marzena Swiderska, Kirsten B. Amaral, Carlos Maurício Antunes, William E. Secor, Rafal P. Witek, José Roberto Lambertucci, Fausto L. Pereira, Anna Mae Diehl

Liver Int. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Liver Int. 2013 Jan; 33(1): 149–161. Published online 2012 Nov 1. doi: 10.1111/liv.12016

PMCID:: PMC3518740

Abstract Article PDF–5.6M

Select item 735130020.

Schistosomiasis Consortium for Operational Research and Evaluation (SCORE): Its Foundations, Development, and Evolution

Daniel G. Colley, Julie A. Jacobson, Sue Binder

Am J Trop Med Hyg. 2020 Jul; 103(1 Suppl): 5–13. Published online 2020 May 12. doi: 10.4269/ajtmh.19-0785

PMCID:: PMC7351300

Abstract Article PDF–130K

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Fig 1Sera and hepatic osteopontin are upregulated in human acute schistosomiasis mansoni.

A) ELISA for osteopontin in the plasma of uninfected controls (NI, n = 21) and schistosomiasis patients with Acute (n = 3), hepatointestinal (n = 26) and hapatosplenic (n = 39) forms of disease. B) ELISA for osteopontin in the serum of uninfected controls (n = 21) and patients with acute schistosomiasis mansoni (n = 28). C) ELISA for osteopontin in the serum of uninfected controls (NI, n = 21) and patients with acute schistosomiasis mansoni (n = 28) grouped by weeks post infection. Medians are displayed; Mann-Whitney U test: #p<0.05, ##p<0.01, ###p<0.001, ####p<0.0001 vs uninfected controls; *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. D) Immunohistochemistry for osteopontin in liver needle biopsy fragment of a representative subject with acute schistosomiasis mansoni (10 weeks post infection). Final magnification 100x, 200x and 400x.

Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni

PLoS Negl Trop Dis. 2016 Oct;10(10):e0005057.
Figure 3Positivity of Schistosomiasis mansoni by Health Region in the Maranhao State, Brazil, 2007 to 2016.

Spatial distribution of the positivity of Schistosomiasis mansoni in Maranhao State, Northeastern Brazil, from 2007 to 2016

Rev Inst Med Trop Sao Paulo. 2022;64:053.
Figure 1Historical series of the positivity rate of schistosomiasis mansoni in the Maranhao State, Brazil, 2007 to 2016.

Spatial distribution of the positivity of Schistosomiasis mansoni in Maranhao State, Northeastern Brazil, from 2007 to 2016

Rev Inst Med Trop Sao Paulo. 2022;64:053.
Fig. 2

Circulating osteopontin is a morbidity biomarker in murine and human schistosomiasis mansoni. Receiver operating characteristics curve analysis of circulating osteopontin levels in murine (A) and human (B) schistosomiasis mansoni. AUROC, area under the ROC curve; CI, confidence interval.

Serum osteopontin is a biomarker of severe fibrosis and portal hypertension in human and murine schistosomiasis mansoni

Int J Parasitol. ;46(13-14):829-832.